Now a peaceful part of the old town, the Vilna Ghetto was a World War II Jewish ghetto established and operated by Nazi Germany in the city of Vilnius in the territory of Nazi-administered Reichskommissariat Ostland.
During the approximately two years of its existence starvation, disease, street executions, maltreatment, and deportations to concentrations and extermination camps reduced the ghetto's population from an estimated 40,000 to zero.
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https://en.wikipedia.org/wiki/Vilna_Ghetto