There has been a recording studio in the basement of No. 22 since Tin Pan Alley Studios was set up by violinist Ralph Elman in 1954. In 1989 Acid Jazz Records moved in. Two years later, Jamiroquai signed to the label and made the industry's record of the year, 'When You Gonna Learn'. Reggae legend Gregory Isaacs recorded his 1995 set ‘Private Lesson’ there. In 2013, producer Guy Katsav took over management of the premises, renaming them Denmark Street Studios.

Sources: Wikipedia, https://www.acidjazz.co.uk/ , https://www.chateaudenmark.com/journal/no-21-25-across-time